×
For best experience we recommend to activate Javascript in your browser.
SMAD3 antibody (AA 186-215)
SMAD3
Reactivity: Human, Mouse
WB, IHC (p), IF, FACS
Host: Rabbit
Polyclonal
RB24758
unconjugated
Product Details anti-SMAD3 Antibody
(hide)
Target
See all SMAD3 Antibodies
SMAD3
(SMAD, Mothers Against DPP Homolog 3 (SMAD3))
Binding Specificity
All epitopes for SMAD3 antibodies
AA 186-215
Reactivity
All reactivities for SMAD3 antibodies
Human, Mouse
Host
All hosts for SMAD3 antibodies
Rabbit
Clonality
All clonalities for SMAD3 antibodies
Polyclonal
Conjugate
All conjugates for SMAD3 antibodies
This SMAD3 antibody is un-conjugated
Application
All applications for SMAD3 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)
Predicted Reactivity
C, Pig, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SMAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from human SMAD3.
Clone
RB24758
Isotype
Ig Fraction
Top Product
Discover our top product SMAD3 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-SMAD3 antibody (ABIN653953)
(hide)
Zhou, Liu, Pan, Du, Li, Ma, Yao, Li, Liu : "The let-7g microRNA promotes follicular granulosa cell apoptosis by targeting transforming growth factor-? type 1 receptor. " in: Molecular and cellular endocrinology , Vol. 409 , pp. 103-12 , (2015 ) (PubMed ).
Lessard, Rivas, Alves-Wagner, Hirshman, Gallagher, Constantin-Teodosiu, Atkins, Greenhaff, Qi, Gustafsson, Fielding, Timmons, Britton, Koch, Goodyear : "Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks. " in: Diabetes , Vol. 62 , Issue 8 , pp. 2717-27 , (2013 ) (PubMed ).
Target Details for SMAD3
(hide)
Target
SMAD3
(SMAD, Mothers Against DPP Homolog 3 (SMAD3))
Alternative Name
SMAD3 (SMAD3 Products )
Background
SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
Molecular Weight
48081
Gene ID
4088
NCBI Accession
NP_001138574 , NP_001138575 , NP_001138576 , NP_005893
UniProt
P84022
Pathways
Cell Division Cycle , Chromatin Binding , Cell-Cell Junction Organization , Positive Regulation of Endopeptidase Activity , Autophagy
Recently viewed
(hide)