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MUTED antibody (AA 40-68)

The Rabbit Polyclonal anti-MUTED antibody has been validated for WB and IHC (p). It is suitable to detect MUTED in samples from Human and Mouse.
Catalog No. ABIN654098

Quick Overview for MUTED antibody (AA 40-68) (ABIN654098)

Target

See all MUTED Antibodies
MUTED (Muted Homolog (MUTED))

Reactivity

  • 18
  • 10
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Mouse

Host

  • 16
  • 2
Rabbit

Clonality

  • 18
Polyclonal

Conjugate

  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
This MUTED antibody is un-conjugated

Application

  • 13
  • 11
  • 8
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB22107
  • Binding Specificity

    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 40-68

    Predicted Reactivity

    Pig

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.

    Isotype

    Ig Fraction
  • Application Notes

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Expiry Date

    6 months
  • Target

    MUTED (Muted Homolog (MUTED))

    Alternative Name

    MUTED

    Background

    This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.

    Molecular Weight

    21609

    Gene ID

    63915

    NCBI Accession

    NP_001186251, NP_958437

    UniProt

    Q8TDH9
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