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PPP1R14C antibody (C-Term)
PPP1R14C
Reactivity: Human, Mouse
WB, IHC (p)
Host: Rabbit
Polyclonal
RB22524
unconjugated
Product Details anti-PPP1R14C Antibody
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Target
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PPP1R14C
(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14C (PPP1R14C))
Binding Specificity
All epitopes for PPP1R14C antibodies
AA 126-155, C-Term
Reactivity
All reactivities for PPP1R14C antibodies
Human, Mouse
Host
All hosts for PPP1R14C antibodies
Rabbit
Clonality
All clonalities for PPP1R14C antibodies
Polyclonal
Conjugate
All conjugates for PPP1R14C antibodies
This PPP1R14C antibody is un-conjugated
Application
All applications for PPP1R14C antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PP1R14C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the C-terminal region of human PP1R14C.
Clone
RB22524
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-PPP1R14C antibody (ABIN654110)
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Xiong, Xia, Tang, Pan, Mei, Xiong : "Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response. " in: EBioMedicine , Vol. 9 , pp. 45-60 , (2016 ) (PubMed ).
Target Details for PPP1R14C
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Target
PPP1R14C
(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14C (PPP1R14C))
Alternative Name
PP1R14C (PPP1R14C Products )
Synonyms
CPI17-like antibody, KEPI antibody, NY-BR-81 antibody, 6330514J04Rik antibody, Kepi antibody, protein phosphatase 1 regulatory inhibitor subunit 14C antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14c antibody, PPP1R14C antibody, Ppp1r14c antibody
Background
The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1, see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied by OMIM].
Molecular Weight
17843
Gene ID
81706
NCBI Accession
NP_112211
UniProt
Q8TAE6
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