FOXL2 antibody (N-Term)

Catalog No. ABIN654125

The Rabbit Polyclonal anti-FOXL2 antibody has been validated for WB and FACS. It is suitable to detect FOXL2 in samples from Human. There is 1 publication available.

Quick Overview for FOXL2 antibody (N-Term) (ABIN654125)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXL2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB22898

Product Details anti-FOXL2 Antibody

Binding Specificity: AA 3-29, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FOXL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-29 amino acids from the N-terminal region of human FOXL2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-FOXL2 antibody (ABIN654125)

Hirano, Wada-Hiraike, Fu, Akino, Isono, Sakurabashi, Fukuda, Morita, Tanikawa, Miyamoto, Nishi, Yanase, Harada, Oishi, Yano, Koga, Oda, Kawana, Fujii, Osuga: "The Emerging Role of FOXL2 in Regulating the Transcriptional Activation Function of Estrogen Receptor β: An Insight Into Ovarian Folliculogenesis." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 24, Issue 1, pp. 133-141, (2017) (PubMed).

Target Details for FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Alternative Name: FOXL2

Background: This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3.

Molecular Weight: 38772

Gene ID: 668

NCBI Accession: NP_075555

UniProt: P58012

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity