L2HGDH antibody (AA 132-159)

Catalog No. ABIN654213

The Rabbit Polyclonal anti-L2HGDH antibody (Clone RB27534) (ABIN654213) specifically detects L2HGDH in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for L2HGDH antibody (AA 132-159) (ABIN654213)

Target: L2HGDH (L-2-Hydroxyglutarate Dehydrogenase (L2HGDH))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L2HGDH antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB27534

Product Details anti-L2HGDH Antibody

Binding Specificity: AA 132-159

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This L2HGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-159 amino acids from the Central region of human L2HGDH.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for L2HGDH

Target: L2HGDH (L-2-Hydroxyglutarate Dehydrogenase (L2HGDH))

Alternative Name: L2HGDH

Background: This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

Molecular Weight: 50316

Gene ID: 79944

NCBI Accession: NP_079160

UniProt: Q9H9P8