CNR2 antibody (C-Term)

Catalog No. ABIN654631

This Rabbit Polyclonal antibody specifically detects CNR2 in WB, FACS and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for CNR2 antibody (C-Term) (ABIN654631)

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNR2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21841

Product Details anti-CNR2 Antibody

Binding Specificity: AA 329-356, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-356 amino acids from the C-terminal region of human CB2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 0.059027777777778. IHC-P: 0.059027777777778. IHC-P: 1:10~50. FC: 1:10~50. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CNR2 antibody (ABIN654631)

Kamikubo, Kai, Tsuji-Naito, Akagawa: "β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes." in: Molecular nutrition & food research, Vol. 60, Issue 10, pp. 2228-2242, (2017) (PubMed).

Hu, Zhou, Wang, Lu, Yin: "N-stearoyl-l-Tyrosine inhibits the cell senescence and apoptosis induced by H2O2 in HEK293/Tau cells via the CB2 receptor." in: Chemico-biological interactions, Vol. 272, pp. 135-144, (2017) (PubMed).

Target Details for CNR2

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Alternative Name: CB2

Background: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

Molecular Weight: 39681

Gene ID: 1269

NCBI Accession: NP_001832

UniProt: P34972