Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Clone
RB22234
Binding Specificity
AA 578-606, C-Term
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ITIH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 578-606 amino acids from the C-terminal region of human ITIH5.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target
ITIH5
(Inter alpha Globulin Inhibitor H5 (ITIH5))
Alternative Name
ITIH5
Background
This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants.