INHBA antibody (N-Term)

Catalog No. ABIN2844710

This Rabbit Polyclonal antibody specifically detects INHBA in WB, IF, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for INHBA antibody (N-Term) (ABIN2844710)

Target: INHBA (Inhibin, beta A (INHBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INHBA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB20703

Product Details anti-INHBA Antibody

Binding Specificity: AA 85-112, N-Term

Predicted Reactivity: B, Hs, M, Rat, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This INHBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-112 amino acids from the N-terminal region of human INHBA.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for INHBA

Target: INHBA (Inhibin, beta A (INHBA))

Alternative Name: INHBA

Background: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Molecular Weight: 47442

Gene ID: 3624

NCBI Accession: NP_002183

UniProt: P08476

Pathways: Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy