TCF21 antibody (C-Term)
Quick Overview for TCF21 antibody (C-Term) (ABIN655524)
Target
See all TCF21 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
 - AA 144-173, C-Term
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Predicted Reactivity
 - B
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Purification
 - This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
 - This TCF21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the C-terminal region of human TCF21.
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Isotype
 - Ig Fraction
 
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Application Notes
 - WB: 1:1000. WB: 1:1000. FC: 1:10~50
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Restrictions
 - For Research Use only
 
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Format
 - Liquid
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Buffer
 - Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
 - Sodium azide
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Precaution of Use
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - 4 °C,-20 °C
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Storage Comment
 - Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
 - 6 months
 
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                                            : "Down-regulation of TCF21 by hypermethylation induces cell proliferation, migration and invasion in colorectal cancer."    in: Biochemical and biophysical research communications, (2015)         (PubMed).        
 
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                                            : "Down-regulation of TCF21 by hypermethylation induces cell proliferation, migration and invasion in colorectal cancer."    in: Biochemical and biophysical research communications, (2015)         (PubMed).        
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- TCF21 (Transcription Factor 21 (TCF21))
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Alternative Name
 - TCF21
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Background
 - TCF21 encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. Two transcript variants encoding the same protein have been found for this gene.
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Gene ID
 - 6943
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NCBI Accession
 - NP_003197, NP_938206
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UniProt
 - O43680
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Pathways
 - Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
 
Target
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