RPGR antibody (AA 744-772)

Catalog No. ABIN656160

The Rabbit Polyclonal anti-RPGR antibody (Clone RB31028) (ABIN656160) specifically detects RPGR in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for RPGR antibody (AA 744-772) (ABIN656160)

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPGR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31028

Product Details anti-RPGR Antibody

Binding Specificity: AA 744-772

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RPGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids of human RPGR.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RPGR Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for RPGR

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Alternative Name: RPGR

Background: This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

Molecular Weight: 113387

Gene ID: 6103

NCBI Accession: NP_000319, NP_001030025

UniProt: Q92834