COX6B1 antibody (C-Term)

Catalog No. ABIN656270

The Rabbit Polyclonal anti-COX6B1 antibody has been validated for WB and IHC (p). It is suitable to detect COX6B1 in samples from Human.

Quick Overview for COX6B1 antibody (C-Term) (ABIN656270)

Target: COX6B1 (Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX6B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32248

Product Details anti-COX6B1 Antibody

Binding Specificity: AA 59-86, C-Term

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COX6B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human COX6B1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: COX6B1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for COX6B1

Target: COX6B1 (Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1))

Alternative Name: COX6B1

Background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.

Molecular Weight: 10192

Gene ID: 1340

NCBI Accession: NP_001854

UniProt: P14854