SEPN1 antibody (C-Term)

Catalog No. ABIN656385

This anti-SEPN1 antibody is a Rabbit Polyclonal antibody detecting SEPN1 in WB and IHC (p). Suitable for Human.

Quick Overview for SEPN1 antibody (C-Term) (ABIN656385)

Target: SEPN1 (Selenoprotein N, 1 (SEPN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEPN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31326

Product Details anti-SEPN1 Antibody

Binding Specificity: AA 417-445, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from the C-terminal region of human SEPN1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SEPN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for SEPN1

Target: SEPN1 (Selenoprotein N, 1 (SEPN1))

Alternative Name: SEPN1

Background: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molecular Weight: 65813

Gene ID: 57190

NCBI Accession: NP_065184, NP_996809

UniProt: Q9NZV5

Pathways: Skeletal Muscle Fiber Development