IRF4 antibody (AA 164-191)

Catalog No. ABIN656568

This anti-IRF4 antibody is a Rabbit Polyclonal antibody detecting IRF4 in WB and FACS. Suitable for Human.

Quick Overview for IRF4 antibody (AA 164-191) (ABIN656568)

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB17417

Product Details anti-IRF4 Antibody

Binding Specificity: AA 164-191

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This IRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-191 amino acids from the Central region of human IRF4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: IRF4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for IRF4

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Alternative Name: IRF4

Background: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 51772

Gene ID: 3662

NCBI Accession: NP_001182215, NP_002451

UniProt: Q15306

Pathways: Chromatin Binding