Myosin 9 antibody

Catalog No. ABIN6566485

Product Details anti-Myosin 9 Antibody

Target: Myosin 9 (MYH9)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin 9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human MYH9

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:2000 IHC 1:50 - 1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myosin 9

Target: Myosin 9 (MYH9)

Alternative Name: MYH9 (MYH9 Products)

Background:

Synonyms: BDPLT 6,BDPLT6,Cellular myosin heavy chain,Cellular myosin heavy chain type A,DFNA 17,DFNA17,EPSTS,FTNS,MGC104539,MHA,MYH 2A,MYH 9,MYH2A,MYH9,MYH9,MYHas8,MyHC 2A,MyHC IIa,MyHC2A,MyHCIIa,MYHSA 2,MYHSA2,Myosin 9,Myosin heavy chain 9,Myosin heavy chain 9 non muscle,Myosin heavy chain,Myosin heavy chain non muscle IIa,Myosin heavy chain nonmuscle IIa,Myosin heavy polypeptide 2,Myosin heavy polypeptide 9 non muscle,Myosin-9,Myosin9,NMHC II A,NMMHC A,NMMHC II a,NMMHC II-a,NMMHC IIA,NMMHC-A,NMMHC-IIA,NMMHCA,Non muscle myosin heavy chain A,Non muscle myosin heavy chain,Non muscle myosin heavy chain II A,Non muscle myosin heavy polypeptide 9,non-muscle IIa,Non-muscle myosin heavy chain A,Non-muscle myosin heavy chain IIa,Nonmuscle myosin heavy chain A,Nonmuscle myosin heavy chain II A,type A

Background: This gene encodes a conventional non-muscle myosin, this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Molecular Weight:

Observed_MW: 250kDa

Calculated_MW: 159kDa/226kDa

Gene ID: 4627

UniProt: P35579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex