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Synonyms: Apoptosis regulator Bcl 2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl2,AW986256,B cell CLL/lymphoma 2,B cell leukemia/lymphoma 2,Bcl-2,Bcl2,BCL2,C430015F12Rik,D630044D05Rik,D830018M01Rik,Leukemia/lymphoma,B-cell,2,Oncogene B-cell leukemia 2,PPP1R50,Protein phosphatase 1,regulatory subunit 50
Background: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.