MAPK3 antibody (Mitogen-Activated Protein Kinase 3)

Details for Product anti-MAPK3 Antibody No. ABIN6566514
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
499
304
285
54
47
43
43
29
19
17
13
11
8
8
7
6
6
4
3
2
2
2
1
1
Host
Rabbit
413
102
8
6
1
Clonality
Polyclonal
Conjugate
This MAPK3 antibody is un-conjugated
33
25
24
15
14
14
9
9
9
9
9
9
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
408
191
184
84
77
63
46
44
39
30
19
14
9
7
3
2
1
1
Options
Immunogen A synthetic peptide of human MAPK3
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name ERK 1 (MAPK3 Antibody Abstract)
Background

Synonyms: ERK 1,ERK,ERK-1,ERK1,ERT 2,ERT2,Extracellular Signal Regulated Kinase 1,Extracellular signal related kinase 1,Extracellular signal-regulated kinase 1,HGNC6877,HS44KDAP,HUMKER1A,Insulin Stimulated MAP2 Kinase,Insulin-stimulated MAP2 kinase,MAP kinase 1,MAP kinase 3,MAP Kinase,MAP kinase isoform p44,MAPK 1,MAPK 3,MAPK,MAPK1,Mapk3,MGC20180,Microtubule Associated Protein 2 Kinase,Microtubule-associated protein 2 kinase,Mitogen Activated Protein Kinase 3,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 3,MK03,OTTHUMP00000174538,OTTHUMP00000174541,p44 ERK1,p44 MAPK,p44-ERK1,p44-MAPK,P44ERK1,P44MAPK,PRKM 3,PRKM3,Protein Kinase Mitogen Activated 3

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Molecular Weight

Observed_MW: 40kDa

Calculated_MW: 38kDa/40kDa/43kDa

Gene ID 5595
UniProt P27361
Pathways MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Mitogen-Activated Protein Kinase 3 (MAPK3) antibody (ABIN6566514) Western blot analysis of extracts of various cell lines, using MAPK3 antibody.
Image no. 2 for anti-Mitogen-Activated Protein Kinase 3 (MAPK3) antibody (ABIN6566514) Immunohistochemistry of paraffin-embedded human kidney using MAPK3 Antibody.
Image no. 3 for anti-Mitogen-Activated Protein Kinase 3 (MAPK3) antibody (ABIN6566514) Immunohistochemistry of paraffin-embedded rat kidney using MAPK3 Antibody.