IGFBP2 antibody

Catalog No. ABIN6566587

This anti-IGFBP2 antibody is a Rabbit Polyclonal antibody detecting IGFBP2 in WB. Suitable for Human, Rat and Mouse.

Quick Overview for IGFBP2 antibody (ABIN6566587)

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IGFBP2 Antibody

Purification: Affinity purification

Immunogen: A synthetic peptide of human IGFBP2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IGFBP2

Target: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Alternative Name: IGFBP2

Background:

Synonyms: BP 2,BP2,IBP 2,IBP-2,IBP2,IBP2,IGF binding protein 2,IGF BP53,IGF-binding protein 2,IGFBP 2,IGFBP-2,IGFBP2,IGFBP53,Insulin like growth factor binding protein 2 36  kDa,Insulin like growth factor binding protein 2,Insulin like growth factor-binding protein 2 precursor ,Insulin-like growth factor-binding protein 2

Background: The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene.

Molecular Weight:

Observed_MW: 37kDa

Calculated_MW: 34kDa

Gene ID: 3485

UniProt: P18065

Pathways: Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation