IRF4 antibody

Catalog No. ABIN6566604

This Rabbit Polyclonal antibody specifically detects IRF4 in WB. It exhibits reactivity toward Mouse and Rat.

Quick Overview for IRF4 antibody (ABIN6566604)

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IRF4 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human IRF4

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IRF4

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Alternative Name: IRF4

Background:

Synonyms: Interferon regulatory factor 4,IRF 4,IRF-4,Irf4,IRF4,LSIRF,Lymphocyte specific interferon regulatory factor,Lymphocyte specific IRF,Lymphocyte-specific interferon regulatory factor,Multiple myeloma oncogene 1,MUM 1,MUM1,NF EM5,NF-EM5,NFEM5,PU.1 interaction partner,Sfpi1/PU.1 interaction partner,Transcriptional activator PIP

Background: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight:

Observed_MW: 52kDa

Calculated_MW: 51kDa

Gene ID: 3662

UniProt: Q15306

Pathways: Chromatin Binding