TJP2 antibody

Catalog No. ABIN6566621

The Rabbit Polyclonal anti-TJP2 antibody (ABIN6566621) specifically detects TJP2 in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TJP2 antibody (ABIN6566621)

Target: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TJP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TJP2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human TJP2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TJP2

Target: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Alternative Name: TJP2

Background:

Synonyms: C9DUPq21.11,DFNA51,DUP9q21.11,Friedreich ataxia region gene X104 (tight junction protein ZO-2),MGC26306 ,PFIC4,Tight junction protein 2,Tight junction protein ZO 2,Tight junction protein ZO-2,TJP2,X104,ZO 2,ZO-2,ZO2,ZO2,Zona occludens 2,Zona occludens protein 2,Zonula occludens protein 2

Background: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Molecular Weight:

Observed_MW: 160kDa

Calculated_MW: 111-137kDa

Gene ID: 9414

UniProt: Q9UDY2