CHRNE antibody

Catalog No. ABIN6566760

This Rabbit Polyclonal antibody specifically detects CHRNE in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CHRNE antibody (ABIN6566760)

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRNE Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human CHRNE

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:4000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHRNE

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Alternative Name: CHRNE

Background:

Synonyms: Acetylcholine receptor subunit epsilon,ACHE,AChR,AchR epsilon subunit,ACHRE,Cholinergic receptor, nicotinic, epsilon polypeptide,Chrne,CMS1D,CMS1E,CMS2A,FCCMS,SCCMS

Background: Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

Molecular Weight:

Observed_MW: 45kDa

Calculated_MW: 54kDa

Gene ID: 1145

UniProt: Q04844