CD53 antibody

Catalog No. ABIN6566768

This Rabbit Polyclonal antibody specifically detects CD53 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for CD53 antibody (ABIN6566768)

Target: CD53

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD53 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD53 Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CD53 (NP_000551.1).

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD53

Target: CD53

Alternative Name: CD53

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 35kDa

Calculated_MW: 24kDa

Gene ID: 963

UniProt: P19397