IL17 Receptor B antibody

Catalog No. ABIN6566793

The Rabbit Polyclonal anti-IL17 Receptor B antibody has been validated for WB. It is suitable to detect IL17 Receptor B in samples from Human, Mouse and Rat.

Quick Overview for IL17 Receptor B antibody (ABIN6566793)

Target: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17 Receptor B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL17 Receptor B Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human IL17RB

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:4000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL17 Receptor B

Target: IL17 Receptor B (IL17RB) (Interleukin 17 Receptor B (IL17RB))

Alternative Name: IL17RB

Background:

Synonyms: CRL 4,CRL4,Cytokine receptor CRL4,EVI 27,EVI27,IL 17 receptor B,IL 17 receptor homolog 1,IL 17B receptor,IL 17RB,IL 17Rh1,IL17BR,IL17RB,IL17RH1,Interleukin 17 receptor B,Interleukin 17 receptor homolog 1,Interleukin 17 receptor homolog,Interleukin 17B receptor,MGC5245

Background: The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.

Molecular Weight:

Observed_MW: 75kDa

Calculated_MW: 31kDa/55kDa

Gene ID: 55540

UniProt: Q9NRM6