HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) antibody

Catalog No. ABIN6566799

The Rabbit Polyclonal anti- antibody has been validated for WB. It is suitable to detect in samples from Human, Mouse and Rat.

Quick Overview for HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) antibody (ABIN6566799)

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Purification: Affinity purification

Immunogen: Recombinant protein of human ERVFRD-1

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:4000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Alternative Name: ERVFRD-1

Background:

Synonyms: Endogenous Retrovirus Group FRD Member 1 Envelope,Endogenous Retrovirus Group FRD Member 1,HERV-FRD_6p24.1 Provirus Ancestral Env Polyprotein,Envelope Polyprotein,ERVFRDE1,HERV-FRD,HERV-FRD Provirus Ancestral Env Polyprotein,Endogenous Retrovirus Group FRD, Member 1,Syncytin 2,HERV-W/FRD,Syncytin-2,GLLL6191,UNQ6191,EnvFRD

Background: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Molecular Weight:

Observed_MW: 38kDa

Calculated_MW: 59kDa

Gene ID: 405754

UniProt: P60508