HINT1 antibody

Catalog No. ABIN6566820

This anti-HINT1 antibody is a Rabbit Polyclonal antibody detecting HINT1 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for HINT1 antibody (ABIN6566820)

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HINT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HINT1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human HINT1

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HINT1

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Alternative Name: HINT1

Background:

Synonyms: Adenosine 5' monophosphoramidase,Adenosine 5''-monophosphoramidase,HINT 1,HINT1,HINT1,Histidine triad nucleotide binding protein 1,Histidine triad nucleotide-binding protein 1,PKCI 1,PKCI-1,PKCI1,PRKCNH1,Protein kinase C inhibitor 1,Protein kinase C interacting protein 1,Protein kinase C-interacting protein 1

Background: This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed.

Molecular Weight:

Observed_MW: 14kDa

Calculated_MW: 13kDa

Gene ID: 3094

UniProt: P49773