Neurexin 3 antibody

Catalog No. ABIN6566846

This Rabbit Polyclonal antibody specifically detects Neurexin 3 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Neurexin 3 antibody (ABIN6566846)

Target: Neurexin 3 (NRXN3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurexin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Neurexin 3 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human NRXN3

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Neurexin 3

Target: Neurexin 3 (NRXN3)

Alternative Name: NRXN3

Background:

Synonyms: C14orf60,KIAA0743,Neurexin 3,Neurexin III,Neurexin III-alpha,Neurexin-3,Neurexin-3-alpha,Neurexin-III-beta,NRXN3

Background: This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.

Molecular Weight:

Observed_MW: 140kDa

Calculated_MW: 43kDa/47kDa/50kDa/69kDa/117kDa/153kDa/180kDa

Gene ID: 9369

UniProt: Q9HDB5, Q9Y4C0