ERAL1 antibody

Catalog No. ABIN6566905

This anti-ERAL1 antibody is a Rabbit Polyclonal antibody detecting ERAL1 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for ERAL1 antibody (ABIN6566905)

Target: ERAL1 (Era G-Protein-Like 1 (ERAL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERAL1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ERAL1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERAL1

Target: ERAL1 (Era G-Protein-Like 1 (ERAL1))

Alternative Name: ERAL1

Background:

Synonyms: CEGA,Conserved ERA like GTPase,Conserved ERA-like GTPase,ERA ,Era (E. coli G protein homolog) like 1,Era G protein like 1 (E. coli) ,Era G protein like 1,ERA W,ERA-like protein 1,ERA-W,Eral1,ERAL1,ERAL1A,ERAW,GTP binding protein era homolog,GTPase Era,GTPase Era, mitochondrial,GTPase human homolog of E. coli essential cell cycle protein Era ,H-ERA,HERA A,hERA,HERA B,HERAA,HERAB,mitochondrial

Background: The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 48kDa

Calculated_MW: 30kDa/48kDa

Gene ID: 26284

UniProt: O75616

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly