Corin antibody

Catalog No. ABIN6566914

This Rabbit Polyclonal antibody specifically detects Corin in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Corin antibody (ABIN6566914)

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Corin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Corin Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human CORIN

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Corin

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Alternative Name: CORIN

Background:

Synonyms: activated protease fragment,ATC 2,ATC2,Atrial natriuretic peptide-converting enzyme,Atrial natriuteric peptide converting enzyme,Corin,Corin serine peptidase,CORIN,CRN,Heart specific serine proteinase,Heart specific serine proteinase ATC2,Heart-specific serine proteinase ATC2,MGC119742,Pro ANP convertase,Pro ANP converting enzyme,Pro-ANP-converting enzyme,TMPRSS 10,TMPRSS10,Transmembrane protease serine 10

Background: This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 116kDa

Calculated_MW: 113kDa/116kDa

Gene ID: 10699

UniProt: Q9Y5Q5

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones