Phospholipase B antibody

Catalog No. ABIN6566925

The Rabbit Polyclonal anti-Phospholipase B antibody has been validated for WB. It is suitable to detect Phospholipase B in samples from Human, Mouse and Rat.

Quick Overview for Phospholipase B antibody (ABIN6566925)

Target: Phospholipase B (PLB)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Phospholipase B Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PLB1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Phospholipase B

Target: Phospholipase B (PLB)

Alternative Name: PLB1

Background:

Synonyms: Calcium dependent phospholipid binding protein,CPLA 2,cPLA2 alpha,cPLA2,Cytosolic phospholipase A2,Cytosolic phospholipase A2 group IVA,Lysophospholipase,MGC126350,PA24A,Phosphatidylcholine 2 acylhydrolase,Phosphatidylcholine 2-acylhydrolase,Phospholipase A2 group 4 A,Phospholipase A2 group IVA (cytosolic calcium dependent),Phospholipase A2 group IVA,PhospholipaseA2,PLA2G4,pla2g4a

Background: This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene.

Molecular Weight:

Observed_MW: 170kDa

Calculated_MW: 47kDa/54kDa/85kDa/161kDa/163kDa

Gene ID: 151056

UniProt: Q6P1J6