PLOD3 antibody

Catalog No. ABIN6566977

The Rabbit Polyclonal anti-PLOD3 antibody (ABIN6566977) specifically detects PLOD3 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PLOD3 antibody (ABIN6566977)

Target: PLOD3 (Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLOD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLOD3 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PLOD3

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLOD3

Target: PLOD3 (Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3))

Alternative Name: PLOD3

Background:

Synonyms: 2-oxoglutarate 5-dioxygenase 3,bone protein I,BP-I,LH3,Lysine hydroxylase 3,Lysyl hydroxylase 3,Plod3,PLOD3,Procollagen lysine,2 oxoglutarate 5 dioxygenase 3 precursor,Procollagen-lysine

Background: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.

Molecular Weight:

Observed_MW: 80kDa

Calculated_MW: 84kDa

Gene ID: 8985

UniProt: O60568