Cadherin 4 antibody

Catalog No. ABIN6566983

The Rabbit Polyclonal anti-Cadherin 4 antibody has been validated for WB. It is suitable to detect Cadherin 4 in samples from Human, Mouse and Rat.

Quick Overview for Cadherin 4 antibody (ABIN6566983)

Target: Cadherin 4 (CDH4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cadherin 4 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human CDH4

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cadherin 4

Target: Cadherin 4 (CDH4)

Alternative Name: R-Cadherin

Background:

Synonyms: CADH4,Cadherin 4,Cadherin-4,cdh4,R CAD,R-CAD,R-cadherin,Retinal cadherin

Background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 100kDa

Calculated_MW: 92kDa/100kDa

Gene ID: 1002

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size