ARHGDIA antibody

Catalog No. ABIN6567345

This Rabbit Polyclonal antibody specifically detects ARHGDIA in WB and IF. It exhibits reactivity toward Human, Mouse and Monkey.

Quick Overview for ARHGDIA antibody (ABIN6567345)

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGDIA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ARHGDIA Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ARHGDIA

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGDIA

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Alternative Name: ARHGDIA

Background:

Synonyms: ARHGDIA,fa96g11,GDIA 1,GDIA1,GDIR1,MGC117248,NPHS8,Rho GDI 1,Rho GDI alpha,Rho GDI,Rho GDP dissociation inhibitor (GDI) alpha,Rho GDP dissociation inhibitor 1,Rho GDP dissociation inhibitor alpha,Rho GDP-dissociation inhibitor 1,Rho-GDI alpha,RhoGDI 1,RhoGDI alpha,RHOGDI,RhoGDI1,wu:fa96g11,zgc:55554,zgc:77681

Background: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 23kDa

Calculated_MW: 18kDa/23kDa

Gene ID: 396

UniProt: P52565

Pathways: Neurotrophin Signaling Pathway