MUL1 antibody (C-Term)

Catalog No. ABIN656738

The Rabbit Polyclonal anti-MUL1 antibody is suitable to detect MUL1 in samples from Human. It has been validated for WB.

Quick Overview for MUL1 antibody (C-Term) (ABIN656738)

Target: MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUL1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB32336

Product Details anti-MUL1 Antibody

Binding Specificity: AA 272-301, C-Term

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MUL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human MUL1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MUL1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for MUL1

Target: MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))

Alternative Name: MUL1

Background: E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Molecular Weight: 39800

Gene ID: 79594

NCBI Accession: NP_078820

UniProt: Q969V5

Pathways: Positive Regulation of Endopeptidase Activity