PLA2G2A antibody

Catalog No. ABIN6567421

The Rabbit Polyclonal anti-PLA2G2A antibody has been validated for WB. It is suitable to detect PLA2G2A in samples from Human and Mouse.

Quick Overview for PLA2G2A antibody (ABIN6567421)

Target: PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLA2G2A Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PLA2G2A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLA2G2A

Target: PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))

Alternative Name: PLA2G2A

Background:

Synonyms: GIIC sPLA2,Group IIA phospholipase A2,membrane associated,MOM1,Non-pancreatic secretory phospholipase A2,NPS-PLA2,OTTHUMP00000002786,PA2GA,Phosphatidylcholine 2-acylhydrolase 2A,Phospholipase A2,Phospholipase A2 group IIA,Phospholipase A2, group IIA (platelets, synovial fluid),PLA2,PLA2B,PLA2G2A,PLA2L,PLA2S,PLAS1,RASF A,sPLA2

Background: The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.

Molecular Weight:

Observed_MW: 18kDa

Calculated_MW: 16kDa

Gene ID: 5320

UniProt: P14555

Pathways: Stem Cell Maintenance, Inositol Metabolic Process