PLA2G2A antibody (AA 21-144)
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- Target See all PLA2G2A Antibodies
- PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))
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Binding Specificity
- AA 21-144
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PLA2G2A antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Phospholipase A2, membrane associated protein (21-144AA)
- Isotype
- IgG
- Top Product
- Discover our top product PLA2G2A Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))
- Alternative Name
- PLA2G2A (PLA2G2A Products)
- Synonyms
- MOM1 antibody, PLA2 antibody, PLA2B antibody, PLA2L antibody, PLA2S antibody, PLAS1 antibody, sPLA2 antibody, EF antibody, Mom1 antibody, Pla2 antibody, sPla2-IIA antibody, phospholipase A2 group IIA antibody, phospholipase A2, group IIA (platelets, synovial fluid) antibody, PLA2G2A antibody, Pla2g2a antibody
- Background
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Background: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
Aliases: EC 3.1.1.4 antibody, GIIC sPLA2 antibody, Group IIA phospholipase A2 antibody, membrane associated antibody, Modifier of MIN 1 mouse homolog antibody, MOM1 antibody, Non-pancreatic secretory phospholipase A2 antibody, NPS PLA2 antibody, NPS-PLA2 antibody, PA2GA_HUMAN antibody, Phosphatidylcholine 2-acylhydrolase 2A antibody, Phosphatidylcholine 2acylhydrolase antibody, Phospholipase A2 antibody, Phospholipase A2 group IIA (platelets, synovial fluid) antibody, Phospholipase A2 membrane associated antibody, Phospholipase A2 polypeptide B antibody, Phospholipase A2 synovial antibody, PLA2 antibody, PLA2B antibody, PLA2G2A antibody, PLA2L antibody, PLA2S antibody, PLAS1 antibody, RASF A antibody, sPLA2 antibody
- UniProt
- P14555
- Pathways
- Stem Cell Maintenance, Inositol Metabolic Process
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