BIRC7 antibody

Catalog No. ABIN6567583

The Rabbit Polyclonal anti-BIRC7 antibody has been validated for WB and IHC. It is suitable to detect BIRC7 in samples from Mouse and Rat.

Quick Overview for BIRC7 antibody (ABIN6567583)

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-BIRC7 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human BIRC7

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Alternative Name: BIRC7

Background:

Synonyms: Baculoviral IAP repeat containing 7,Baculoviral IAP repeat containing protein 7,Baculoviral IAP repeat-containing protein 7,BIRC 7,birc7,BIRC7,KIAP,Kidney inhibitor of apoptosis protein,Livin,Livin inhibitor of apotosis,Melanoma inhibitor of apoptosis protein,ML IAP,ML-IAP,MLIAP,RING finger protein 50,RNF 50,RNF50

Background: This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants

Molecular Weight:

Observed_MW: 35kDa

Calculated_MW: 30kDa/32kDa

Gene ID: 79444

UniProt: Q96CA5