SCARB2 antibody

Catalog No. ABIN6567626

The Rabbit Polyclonal anti-SCARB2 antibody has been validated for WB. It is suitable to detect SCARB2 in samples from Human, Mouse and Rat.

Quick Overview for SCARB2 antibody (ABIN6567626)

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCARB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SCARB2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SCARB2

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:3000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SCARB2

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Alternative Name: SCARB2

Background:

Synonyms: 85 kDa lysosomal membrane sialoglycoprotein,85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2,AMRF,CD36,CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II),CD36 antigen,CD36 antigen-like 2,CD36L2,EPM4,HLGP85,LGP85,LIMP 2,LIMP II,LIMP2,LIMPII,Lysosomal integral membrane protein II,Lysosome membrane protein 2,Lysosome membrane protein II,OTTHUMP00000160590,OTTHUMP00000219176,Scarb2,Scavenger receptor class B member 2,Scavenger receptor class B, member 2,SCRB2,SR BII,SRBII

Background: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 80kDa

Calculated_MW: 37kDa/54kDa

Gene ID: 950

UniProt: Q14108