Melatonin Receptor 1A antibody

Catalog No. ABIN6567742

The Rabbit Polyclonal anti-Melatonin Receptor 1A antibody has been validated for IHC. It is suitable to detect Melatonin Receptor 1A in samples from Human, Mouse and Rat.

Quick Overview for Melatonin Receptor 1A antibody (ABIN6567742)

Target: Melatonin Receptor 1A (MTNR1A)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Melatonin Receptor 1A Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human MTNR1A (NP_005949.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: MTNR1A

Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Molecular Weight:

Observed_MW: 39kDa

Calculated_MW: 39kDa

Gene ID: 4543

UniProt: P48039