Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Clone
RB32610
Binding Specificity
AA 1-30, N-Term
Predicted Reactivity
M
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SEC62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEC62.
TLOC1
Reactivity: Human, Mouse, Rat
IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 750
Application Notes
WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
SEC62 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date
6 months
Target
SEC62 (TLOC1)
(Translocation Protein 1 (TLOC1))
Alternative Name
SEC62
Background
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.