LLGL2 antibody

Catalog No. ABIN6567878

Product Details anti-LLGL2 Antibody

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LLGL2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: A synthetic peptide of mouse LLGL2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LLGL2

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Alternative Name: LLGL2 (LLGL2 Products)

Background:

Synonyms: HGL,Human giant larvae homolog,L2GL2,L2GL2,Lethal 2 giant larvae protein homolog 2,Lethal giant larvae homolog 2,Lethal(2) giant larvae protein homolog 2,LGL2,LLGL2

Background: The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: 114kDa

Calculated_MW: 114kDa

Gene ID: 217325

UniProt: Q3TJ91

Pathways: WNT Signaling