ARIP4 antibody

Catalog No. ABIN6568064

The Rabbit Polyclonal anti-ARIP4 antibody has been validated for IF. It is suitable to detect ARIP4 in samples from Human.

Quick Overview for ARIP4 antibody (ABIN6568064)

Target: ARIP4 (RAD54L2) (RAD54-Like 2 (RAD54L2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARIP4 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-ARIP4 Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human RAD54L2 (NP_055921.2).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARIP4

Target: ARIP4 (RAD54L2) (RAD54-Like 2 (RAD54L2))

Alternative Name: RAD54L2

Background: Adrenergic receptors (ARs) include four general types (a1, a2, b1 and b2) that are found in different target tissues and differ in their affinities and responses to various agonists and antagonists. The coupling of ARs to specific intracellular effectors is mediated through diverse heterotrimeric G proteins. ARs play a critical role in the development of prostate cancer, and transcriptional activity of AR is partly regulated by coregulatory proteins. RAD54L2 (RAD54-like 2), also known as ARIP4 (androgen receptor-interacting protein 4), HSPC325 or SRISNF2L, is a 1,467 amino acid nuclear protein belonging to the SNF2/RAD54 helicase family that consists of one helicase ATP-binding domain and a helicase C-terminal domain. RAD54L2 is a DNA helicase that regulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. RAD54L2 is post-translationally sumoylated or phosphorylated upon DNA damage.

Molecular Weight:

Calculated_MW: 162kDa

Gene ID: 23132

UniProt: Q9Y4B4