IRF8 antibody

Catalog No. ABIN6568119

The Rabbit Polyclonal anti-IRF8 antibody (ABIN6568119) specifically detects IRF8 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for IRF8 antibody (ABIN6568119)

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-IRF8 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human IRF8

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IRF8

Target: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Alternative Name: IRF8

Background:

Synonyms: H ICSBP,H-ICSBP,HGNC:5358,HICSBP,ICSBP 1,ICSBP,ICSBP1,Interferon consensus sequence binding protein 1,Interferon consensus sequence binding protein,Interferon consensus sequence-binding protein,Interferon regulatory factor 8,IRF 8,IRF-8,Irf8,IRF8,MYLS

Background: Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Molecular Weight:

Observed_MW: 54kDa

Calculated_MW: 48kDa

Gene ID: 3394

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin