EPS8 antibody

Catalog No. ABIN6568452

The Rabbit Polyclonal anti-EPS8 antibody (ABIN6568452) specifically detects EPS8 in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for EPS8 antibody (ABIN6568452)

Target: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPS8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPS8 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human EPS8

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EPS8

Target: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Alternative Name: EPS8

Background:

Synonyms: Epidermal growth factor receptor kinase substrate 8,Epidermal growth factor receptor pathway substrate 8,EPS 8,EPS8,EPS8

Background: This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Molecular Weight:

Observed_MW: 100kDa

Calculated_MW: 62kDa/91kDa

Gene ID: 2059

UniProt: Q12929

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization