Cytohesin 4 antibody

Catalog No. ABIN6568509

This anti-Cytohesin 4 antibody is a Rabbit Polyclonal antibody detecting Cytohesin 4 in WB. Suitable for Mouse and Rat.

Quick Overview for Cytohesin 4 antibody (ABIN6568509)

Target: Cytohesin 4 (CYTH4)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytohesin 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cytohesin 4 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human CYTH4

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cytohesin 4

Target: Cytohesin 4 (CYTH4)

Alternative Name: CYTH4

Background:

Synonyms: AI467541,CYH4,CYT4,Cyth4,Cytohesin 4,Cytohesin-4,DJ63G5.1,FLJ00017,PH,PH, SEC7 and coiled coil domain containing protein 4,Pleckstrin homology, SEC7, AND coiled coil domains protein 4,Pscd4,RGD1564842,SEC7 and coiled-coil domain-containing protein 4

Background: This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight:

Observed_MW: 46kDa

Calculated_MW: 45kDa

Gene ID: 27128

UniProt: Q9UIA0