SH3GLB1 antibody

Catalog No. ABIN6568512

This anti-SH3GLB1 antibody is a Rabbit Polyclonal antibody detecting SH3GLB1 in WB. Suitable for Mouse and Rat.

Quick Overview for SH3GLB1 antibody (ABIN6568512)

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3GLB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SH3GLB1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human SH3GLB1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SH3GLB1

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Alternative Name: SH3GLB1

Background:

Synonyms: Bax interacting factor 1,Bax-interacting factor 1,Bif 1,Bif-1,CGI 61,dJ612B15.2,Endophilin B1,Endophilin-B1,PPP1R70,Protein phosphatase 1 regulatory subunit 70,SH3 containing protein SH3GLB1,SH3 domain GRB2 like endophilin B1,SH3 domain-containing GRB2-like protein B1,Sh3glb1,SH3p13,SHLB1

Background: This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 41kDa

Calculated_MW: 29kDa/40kDa/43kDa

Gene ID: 51100

UniProt: Q9Y371

Pathways: Autophagy