MRPL50 antibody (C-Term)

Catalog No. ABIN656854

This Rabbit Polyclonal antibody specifically detects MRPL50 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for MRPL50 antibody (C-Term) (ABIN656854)

Target: MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL50 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB27656

Product Details anti-MRPL50 Antibody

Binding Specificity: AA 119-147, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RM50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-147 amino acids from the C-terminal region of human RM50.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RM50 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for MRPL50

Target: MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))

Alternative Name: RM50

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.

Molecular Weight: 18325

Gene ID: 54534

NCBI Accession: NP_061924

UniProt: Q8N5N7