VAV3 antibody

Catalog No. ABIN6568678

Product Details anti-VAV3 Antibody

Target: VAV3 (Vav 3 Oncogene (VAV3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAV3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human VAV3 (NP_006104.4).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for VAV3

Target: VAV3 (Vav 3 Oncogene (VAV3))

Alternative Name: VAV3 (VAV3 Products)

Synonyms: RGD1565941 antibody, A530094I06Rik antibody, AA986410 antibody, Idd18.1 antibody, vav guanine nucleotide exchange factor 3 antibody, vav 3 guanine nucleotide exchange factor antibody, vav 3 oncogene antibody, VAV3 antibody, Vav3 antibody

Background: VAV3,This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight:

Observed_MW: 105kDa

Calculated_MW: 32kDa/86kDa/97kDa/100kDa

Gene ID: 10451

UniProt: Q9UKW4

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway