UPB1 antibody

Catalog No. ABIN6568711

The Rabbit Polyclonal anti-UPB1 antibody (ABIN6568711) specifically detects UPB1 in WB. The antibody is reactive with Mouse and Rat samples.

Quick Overview for UPB1 antibody (ABIN6568711)

Target: UPB1 (Ureidopropionase, beta (UPB1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UPB1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human UPB1

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UPB1

Target: UPB1 (Ureidopropionase, beta (UPB1))

Alternative Name: UPB1

Background:

Synonyms: AI195023,Beta alanine synthase,Beta ureidopropionase,BUP1,N carbamoyl beta alanine amidohydrolase,Ureidopropionase, beta

Background: This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.

Molecular Weight:

Observed_MW: 43kDa

Calculated_MW: 43kDa

Gene ID: 51733

UniProt: Q9UBR1