RAP1A antibody (C-Term)

Catalog No. ABIN656873

The Rabbit Polyclonal anti-RAP1A antibody has been validated for WB. It is suitable to detect RAP1A in samples from Mouse.

Quick Overview for RAP1A antibody (C-Term) (ABIN656873)

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP1A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB31718

Product Details anti-RAP1A Antibody

Binding Specificity: AA 142-170, C-Term

Predicted Reactivity: B, Rat, C, Zf, H, Pr, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-170 amino acids from the C-terminal region of human RAP1A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RAP1A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for RAP1A

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Alternative Name: RAP1A

Background: The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50 % amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

Molecular Weight: 20987

Gene ID: 5906

NCBI Accession: NP_001010935, NP_002875

UniProt: P62834

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor