PON2 antibody (N-Term)

Catalog No. ABIN656876

The Rabbit Polyclonal anti-PON2 antibody has been validated for WB, FACS and IHC (p). It is suitable to detect PON2 in samples from Human.

Quick Overview for PON2 antibody (N-Term) (ABIN656876)

Target: PON2 (Paraoxonase 2 (PON2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31960

Product Details anti-PON2 Antibody

Binding Specificity: AA 79-107, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PON2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the N-terminal region of human PON2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PON2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for PON2

Target: PON2 (Paraoxonase 2 (PON2))

Alternative Name: PON2

Background: This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 39381

Gene ID: 5445

NCBI Accession: NP_000296

UniProt: Q15165