Frataxin antibody

Catalog No. ABIN6568875

This anti-Frataxin antibody is a Rabbit Polyclonal antibody detecting Frataxin in WB, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for Frataxin antibody (ABIN6568875)

Target: Frataxin (FXN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Frataxin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Frataxin Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human FXN

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Frataxin

Target: Frataxin (FXN)

Alternative Name: FXN

Background:

Synonyms: CyaY,d-FXN,FA,FARR,Frataxin mature form,Frataxin(81-210),FRDA,FRDA,Friedreich ataxia protein,Fxn,i-FXN,m56-FXN,m78-FXN,m81-FXN,MGC57199,X25

Background: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 14kDa

Calculated_MW: 19kDa/21kDa/23kDa

Gene ID: 2395

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size